GENEALOGY-DNA-L ArchivesArchiver > GENEALOGY-DNA > 2008-02 > 1202102718
From: "steven perkins" <>
Subject: [DNA] Article: Maternal Footprints of Southeast Asians in NorthIndia.
Date: Mon, 4 Feb 2008 00:25:18 -0500
Maternal Footprints of Southeast Asians in North India.
Kumarasamy Thangaraj, Gyaneshwer Chaubey, Toomas Kivisild, Deepa Selvi
Rani, Vijay Kumar Singh, Thanseem Ismail, Denise Carvalho-Silva, Mait
Metspalu, L V K S Bhaskar, Alla G Reddy, Sarat Chandra, Veena Pande, B
Prathap Naidu, Niharika Adarsh, Abhilasha Verma, Inaganti Amara
Jyothi, Chandana Basu Mallick, Nidhi Shrivastava, Ragala Devasena,
Babita Kumari, Amit Kumar Singh, Shailendra Kumar Dhar Dwivedi,
Shefali Singh, Geeta Rao, Pranav Gupta, Vartika Sonvane, Kavita
Kumari, Afsar Basha, K R Bhargavi, Albert Lalremruata, Arvind Kumar
Gupta, Gurukamal Kaur, K K Reddy, A Papa Rao, Richard Villems, Chris
Tyler-Smith, and Lalji Singh
Centre for Cellular and Molecular Biology, Hyderabad, India.
Hum Hered, January 28, 2008; 66(1): 1-9.
We have analyzed 7,137 samples from 125 different caste, tribal and
religious groups of India and 99 samples from three populations of
Nepal for the length variation in the COII/tRNA(Lys) region of mtDNA.
Samples showing length variation were subjected to detailed
phylogenetic analysis based on HVS-I and informative coding region
sequence variation. The overall frequencies of the 9-bp deletion and
insertion variants in South Asia were 1.9 and 0.6%, respectively. We
have also defined a novel deep-rooting haplogroup M43 and identified
the rare haplogroup H14 in Indian populations carrying the 9-bp
deletion by complete mtDNA sequencing. Moreover, we redefined
haplogroup M6 and dissected it into two well-defined subclades. The
presence of haplogroups F1 and B5a in Uttar Pradesh suggests minor
maternal contribution from Southeast Asia to Northern India. The
occurrence of haplogroup F1 in the Nepalese sample implies that Nepal
might have served as a bridge for the flow of eastern lineages to
India. The presence of R6 in the Nepalese, on the other hand, suggests
that the gene flow between India and Nepal has been reciprocal.
Copyright (c) 2008 S. Karger AG, Basel.
Steven C. Perkins
Online Journal of Genetics and Genealogy
Steven C. Perkins' Genealogy Page
|[DNA] Article: Maternal Footprints of Southeast Asians in NorthIndia. by "steven perkins" <>|