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Archiver > GENEALOGY-DNA > 2008-02 > 1203922919


From: "Tim Janzen" <>
Subject: Re: [DNA] 23ANDme versus deCODEme - R1b1c9's
Date: Sun, 24 Feb 2008 23:01:59 -0800
In-Reply-To: <000d01c87736$dd05bfe0$97113fa0$@rr.com>


Dear Eldon,
Thanks for sharing this list of SNPs. We need to keep in mind that
rs2032624 (position 13535818) is not a SNP within R1b since the portion of
the HUGO reference sequence adjacent to this position was from a male from
haplogroup G (see
http://archiver.rootsweb.com/th/read/GENEALOGY-DNA/2007-12/1199141898).
I took a look at the list of 132 Y SNPs that Watson and Ventor share
with the list of the 1418 Y SNPs included on the Illumina chip that deCODEme
uses compiled by David Wilson that is found at
http://www.m222.net/deCODE-Illumina-SNPS_Y-mtDNA.xls. I found that there
are 14 SNPs that Watson and Ventor share that are included in the list of
the Y SNPs on the Illumina chip that deCODEme uses. These SNPs are as
follows:

rs22531092721694
rs27553715367435
rs25008525909423
rs70672757424282
rs169812938856078
rs12640788865525
rs274098112943108
rs271325412979419
rs789305213373585
rs3510830513465511
rs978617116370123
rs653060319613055
rs706734820411776
rs3427630020616699

Thus, there are 5 SNPs on the Illumina chip that Watson and Ventor
share that you don't share for one reason or another. I am not sure why you
don't share these SNPs. I suspect that you may actually have some or all 5
of these SNPs, but that the chip's read on your DNA came up negative or
inconclusive for one reason or another. You seem to be more closely related
to Ventor than you are to Watson since you have 4 SNPs you share with Ventor
that you don't share with Watson.
It would be nice to try to figure out where the above 14 SNPs are
placed on the Y SNP tree. It would particularly be interesting to know
which of these are upstream from S21 and which (if any) are downstream from
S21.
I would also be interested in knowing the 14 SNPs that you have that
you do not share with either Dr. Venter or Dr. Watson if you would be
willing to share that information. I would also like your thoughts as to
why you got results back for only 847 Y SNPs, when there are 1418 Y SNPs on
the Illumina chip. Were the results for the other 571 SNPs inconclusive?
If so, this might help explain why there were 5 SNPs that Watson and Ventor
share that you didn't have. These 5 SNPs may have been among the 571 SNPs
that were inconclusive.
Does anyone else who is in R1b1c have Y SNP data back from deCODEme?
If so, I would be interested in reviewing the data. I would like to compare
the data to Eldon's SNPs, as well as to Watson's and Ventor's SNPs. It
would particularly be helpful to review the results from someone who is in
R1b1c (M269+), but who is S21 negative.
Sincerely,
Tim Janzen

-----Original Message-----
From:
[mailto:] On Behalf Of Eldon Wade
Sent: Sunday, February 24, 2008 2:45 PM
To:
Subject: [DNA] 23ANDme versus deCODEme - R1b1c9's

Tim,

Below are the Y-SNP variations (from the HUGO reference sequence) that I
share with both Dr Venter and Dr Watson or just Dr Venter.

rs2253109A/GY2721694GBoth
rs13305092A/GY8146815AVenter
rs16981293C/TY8856078T*Both
rs1264078A/GY8865525GBoth
rs13304202A/GY12926224AVenter
rs2740981A/GY12943108ABoth
rs7893052C/TY13373585CBoth
rs35108305A/CY13465511ABoth
rs2032624A/CY13535818CBoth
rs9786171A/GY16370123GBoth
rs9786021A/CY16460661AVenter
rs7067348C/TY20411776CBoth
rs34276300A/CY20616699CBoth
rs13303620G/TY20681778TVenter

Eldon

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