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Archiver > GENEALOGY-DNA > 2008-02 > 1204349726
From: "David Wilson" <>
Subject: Re: [DNA] Comparison of deCODEme results for the Y-chromosomeofR1b1c7and R1b1c9 individuals
Date: Fri, 29 Feb 2008 21:35:26 -0800
References: <PM.18192.1204335316@hmweb6.uk1.bibliotech.net>
In-Reply-To: <PM.18192.1204335316@hmweb6.uk1.bibliotech.net>
I should have asked this question in my earlier reply. What is our current
understanding of the HUGO Y-chromosome? I think we have established that it
represents multiple sources from different haplogroups, but have we
established how many individuals or how many haplogroups?
David
-----Original Message-----
From:
[mailto:] On Behalf Of Gareth Henson
Sent: Friday, February 29, 2008 5:35 PM
To:
Subject: Re: [DNA] Comparison of deCODEme results for the Y-chromosome
ofR1b1c7and R1b1c9 individuals
David
I have been given access to results from an individual in haplogroup G5 and
I have been given permission to report to the list that for rs34276300 he
has the C allele - in common with all the R1b1c9 results (including Venter
and Watson). In the results I am aware of, only your R1b1c7 individual and
the HUGO reference sequence have the A allele. This suggests that the C
allele is ancestral and the A allele is derived, which means that this SNP
could be associated with M222 (either equivalent or just upstream or
downstream of it).
I had not noticed this before, but M222 is in the AZFa region which was
sequenced separately, so the fact that the reference sequence is negative
for M222 doesn't tell us anything about the M222 status of the main donor.
There may be other explanations for this SNPs odd results so any additional
data, from inside and outside R1b1c, will be very useful.
Gareth
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