GENEALOGY-DNA-L Archives

Archiver > GENEALOGY-DNA > 2008-06 > 1212973513


From: "Alfred A. Aburto Jr." <>
Subject: Re: [DNA] Generations2 program and the CMH-12 extended haplotypes...
Date: Sun, 08 Jun 2008 18:05:13 -0700
References: <936471110806080753k1912d8e7s787d45c8d71666a@mail.gmail.com><009f01c8c97a$e40205b0$6400a8c0@Ken1> <484C0D1B.90109@sbcglobal.net><00f801c8c988$87da6030$6400a8c0@Ken1>
In-Reply-To: <00f801c8c988$87da6030$6400a8c0@Ken1>


:-)
I should listen to Ken more carefully! I just deleted the 38-67 marker
data. I didn't delete the entire columns! Thanks Ken, for getting me right!

With the 66 J1 Cohen haplotypes having 37 markers tested the MRCA age
came out as 78.03829 generations or ~2300+/-??? years ago (using 30
years per generation). This is "significantly" different (depends on the
confidence interval) than the 29 J1 Cohen haplotypes having 67 markers
tested (MRCA age was ~1700 years ago). So, clearly more data of the
"right" kind (J1 Cohen's) is needed, we really need to get more J1
Cohen's to test at least 37 markers, but 67 would be best if at all
possible!
Al


> Ken Nordtvedt wrote:
> You should be able to proceed with your 37 marker set. Just delete the
> columns for markers 38-67
>
> Make sure your 1 to 37 are aligned correctly. Then you should get an
> output. I really don't know what went wrong with your attempt.
>
>
> ----- Original Message -----
> From: "Alfred A. Aburto Jr." <>
> To: <>; "'Bonnie Schrack'"
> <>; <>
> Sent: Sunday, June 08, 2008 10:47 AM
> Subject: [DNA] Generations2 program and the CMH-12 extended haplotypes ...
>
>
>
>> Ken,
>> Thank you for all your work! I have downloaded your Generations2
>> program. I hope it is the right one to use. I took 29 CMH-12 extended
>> haplotypes (67 markers) from Bonnie Schrack's Y-DNA J website
>> (http://www.familytreedna.com/public/Y-DNA_J/) where she has a J1 clade
>> called "J1 w/22-22 Cohen" (the "22-22" means YCAII=22-22 as modal for
>> this clade) and from Ariel Cohen's Cohen DNA Project
>> (http://www.familytreedna.com/public/Cohen/) to put in your spreadsheet
>> calculator. Also I found a few others in Ysearch that had the CMH-12 or
>> were "close" to to the 67 marker extended haplotypes. These are
>> basically all the 67 marker extended CMH-12 cases I could find. This
>> group of 29 CMH-12 extended haplotypes had the CMH-12 as modal. I made
>> sure to line up all the markers properly. I added a gap between the 37
>> marker limit at column "AN". The result came out as G*(A) = 55.62958
>> generations or using 30 years per generation as 1668.9 years ago (call
>> it 1700 years ago). The confidence interval is something I am not sure
>> about and I would have to rely on you for that answer. So the CMH-12
>> extended haplotypes appear to have an MRCA age of about 1700 years ago.
>> This seems very reasonable from just looking at these haplotypes as they
>> are tightly grouped with a maximum mismatch of 15 markers out of 67.
>>
>> To make sure the variance is accurate, and thus the age, additional
>> known J1 Cohen's testing 67 markers are needed!
>>
>> I have a set of 66 J1 extended CMH-12 haplotypes having 37 markers, but
>> the Generations2 program _did_not_ work with them. G*(A) was #DIV/0!.
>> This larger set of CMH-12 37 marker extended haplotypes would lend
>> support to the above MRCA age if a similar result was obtained (fewer
>> markers but more haplotypes).
>> Al
>>

This thread: