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Archiver > GENEALOGY-DNA > 2008-07 > 1215793378


From: "John E. Mellick" <>
Subject: Re: [DNA] calibrating for common ancestor - QUESTION?
Date: Fri, 11 Jul 2008 12:22:58 -0400
In-Reply-To: <mailman.89372.1215791041.8264.genealogy-dna@rootsweb.com>


Sandy,
Ken mentioned there is a difference between Modal haplotype (most common
allele at each loci, determined independently from the others) and the
founding haplotype. To better understand this difference, you might enjoy
reading Kerchner's method of determining the deduced ancestral haplotype,
using triangulation. See:
http://www.kerchner.com/triangulation.htm
JohnM

>Ken said:
>The founding haplotype needs to be known and used for the mentioned
>variance. It could differ from the modal haplotype of the sample
>population. I know it is reasonable to estimate that founding haplotype
>from the modal haplotype in most cases, but it is important to remember the
>distinction and that they sometimes will differ. One can play around and
>quantify how much error in G estimation one will make if an error on one or
>more markers is made in picking the founding haplotype.
>Ken

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