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Archiver > GENEALOGY-DNA > 2008-08 > 1217811912


From: Gary Felix <>
Subject: Re: [DNA] The Basques and the T-13910 Lactase Persistence Alleles
Date: Sun, 3 Aug 2008 18:05:12 -0700 (PDT)
In-Reply-To: <001d01c8f57d$0bfd5cd0$6501a8c0@Richard>


If the allele did originate in the east as recently as this paper states then why is it most prevalent in the Basque pop. and NW Europe and the Fulani who are thought to be descendants of an early migration (during the greening of the Sahara more than 6K years ago to about 12K http://www.abc.net.au/science/articles/2008/05/09/2240138.htm) of R1b1 males.

It would have expanded with the Neolithic out of the South East.

Gary
Mexico DNA Project Admin.

"R. Stevens" <> wrote:

"Recent genetic research on worldwide distribution of the mutation that created lactose tolerance, which made a dairy-based diet possible, indicates that it probably emerged first in the steppes west of the Ural Mountains between 4600 and 2800 BCE - the late Eneolithic (Mikhailovka I) and the EBA [Early Bronze Age] Yamnaya periods."

In a 2007 study entitled, "Evidence of Still-Ongoing Convergence Evolution of the Lactase Persistence T-13910 Alleles in Humans," Enattah et al found a sample of 85 Basques to carry the T-13910 lactase persistence allele at a frequency of ~92%: http://tinyurl.com/3j2zht .

Is such a level of the T-13910 lactase persistence allele consistent with a population that is supposed to be an isolated Paleolithic remnant?

Perhaps this indicates that the Basques got the T-13910 LP allele someplace farther east before settling down where they are now, and that they settled in where they are now a lot later than we used to think?

Rich


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