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Subject: [DNA] Craig Venter's Exome
Date: Fri, 15 Aug 2008 22:36:03 EDT


Exome seems to be a relatively recent term, first appearing in Google Scholar
(in its current usage) in 2007. It refers to the part of the genome (~1%)
that codes for proteins -- the exons within the boundaries of a gene.


http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1000160

Side note: George Church's Personal Genome Project is starting with the
exomes of 10 people. That will give us more insight into common SNPs (as tested by
deCODEme and 23andMe) vs private/familial SNPs. Of course, the non-exome
portion of the genome will harbor many more SNPs (absolute and percentage-wise) in
both categories. Perhaps we will call it the HyperVariable Region of the
genome :)

Ann Turner



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