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Archiver > GENEALOGY-DNA > 2008-09 > 1221440036


From: "David Faux" <>
Subject: Re: [DNA] 9RA autosomal Native American marker
Date: Sun, 14 Sep 2008 17:53:56 -0700
References: <BLU126-DAV8BE82C64F3E07C5644BC792540@phx.gbl><ea3bd9560809090857y6dbab028u10debbf7a09819e1@mail.gmail.com><REME20080909144237@alum.mit.edu><BLU126-DAV3DF85D72DA4BD6BAE6B3692540@phx.gbl><REME20080909160129@alum.mit.edu><BLU126-DAV7C76E5E2A130ECFFF1E9992540@phx.gbl>
In-Reply-To: <BLU126-DAV7C76E5E2A130ECFFF1E9992540@phx.gbl>


List:

I posted a Google map of the distribution of the 19/20 variant of this
marker, which I also sent to the author of the original journal article, but
I cannot find the specific posting here, so below is the essence of what I
wrote, including the URL to the map.

What has struck me as quite amazing is its "fit" to the data (including maps
and movies) shown in the Hellenthal et al. (2008) article which focuses on
the same population groups in the Schroeder paper. Here is the URL for the
article (the movies can be found via the standard version of the full
article, but for a "crisp" copy of the article free of charge just click on
pdf version).

http://www.plosgenetics.org/article/fetchArticle.action?articleURI=info:doi/10.1371/journal.pgen.1000078


I also wrestled with trying to decide if the Makrani represent a back
migration to Africa from SW Asia. I will likely amend the Google map to
reflect this scenario.

To put it into context, here is the description of what I have observed and
noted previously:

I have created a Google Map to show the geographical distribution of the
19/20 variant of D9S1120. It is only a "rough draft" for now, but shows the
linear pattern being seen in most of the Northern Pakistani tribes and the
area which seems to have been a staging point for population movement to the
Americas via Beringia the Yakut and surrounding people. Then in the Americas
it has an interesting distribution pattern across the entire northernmost
tier, and south to the Yucatan Penninsula but not seen at all in Central or
South America - strictly North American. The lines are just a join the dots
exercise to show how it is "as if" the variant was following a pathway to
the east. There is no deviation from this line, for example no one in all
the European samples had either 19 or 20 (the largest repeat value).

The URL is http://tinyurl.com/5ukqrl

What is presented is entirely tentative since we don't know if the variant
is identical by descent or identical by state. The only way to tell would be
to do a haplotype block analysis sequencing about 80 kb around the marker.
Apparently this has already been done and is likely to appear in an upcoming
publication. Hence nothing can be concluded at this stage except it the
present distribution is along a path that reaches from Africa through the
southern part of Central Asia to North America - very unusual if it is just
coincidence.

David K. Faux.

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