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From: "RICHARD KENYON" <>
Subject: Re: [DNA] Y chromosome map markers - danger zones?
Date: Sat, 18 Oct 2008 22:03:03 -0700
References: <c8e.2b74b8a2.362b7a9b@aol.com><48FA30E2.9020604@san.rr.com><BAY103-DS5A797551C05A3FE261DC4C82C0@phx.gbl><48FAB32C.3020404@san.rr.com>
In-Reply-To: <c8e.2b74b8a2.362b7a9b@aol.com><48FA30E2.9020604@san.rr.com><BAY103-DS5A797551C05A3FE261DC4C82C0@phx.gbl><48FAB32C.3020404@san.rr.com>


The dark bands result from staining a sample and are called euchromatin. The Skaletsy et al. paper of 2003 (referenced by me previously) has a section entitled: Three classes of sequences in the MSY euchromatin. The first paragraph reads: "We find that nearly all of the euchromatin sequences fall into three classes, which we have named X-transposed, X-degenerate and ampliconic. As shown in Figs. 1 and 2, the MSY euchromatin is a patchwork of these three sequence classes. The characteristics of the three classes are summarized in Fig. 4."

The authors prefer to use the term MSY (male-specific Y) instead of NRY (non-recombining Y) because "our discovery of abundant recombination, as reported here and the accompanying manuscript, compels us to rename it the male-specific region or MSY. The MSY is flanked on both sides by pseudoautosomal regions, where X-Y crossing over is a normal and frequent event in male meiosis (see Supplementary Note 1)."

As far as I can tell, the only portion of the Y that the 23andMe v. 2 chip looks at is in the MSY region.


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