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Archiver > GENEALOGY-DNA > 2008-11 > 1226263791
From: Vincent Vizachero <>
Subject: Re: [DNA] L21 and P66
Date: Sun, 9 Nov 2008 15:49:51 -0500
References: <004101c94281$ad13f330$0201a8c0@Richard><ea3bd9560811090822s2f631ff6t8595f4ba9eb63c4f@mail.gmail.com><e2f96c1b0811090825x43f8b8d0vb01a901afd8f465@mail.gmail.com><ea3bd9560811090828l54f35083kb3930e94d513bf00@mail.gmail.com><003201c94289$a0368490$6400a8c0@Ken1><ea3bd9560811090845h5a7af7e6t27e325ef732035de@mail.gmail.com><00a201c9428b$b6fa8ad0$0201a8c0@Richard><ea3bd9560811090858v2668f4f7s965a513ba09e5ec8@mail.gmail.com><00c501c9428e$0f09f5b0$0201a8c0@Richard><000a01c9428e$dcef9d90$6400a8c0@Ken1><00d901c94291$9ce9d0f0$0201a8c0@Richard><002901c94292$9f562090$6400a8c0@Ken1> <00e601c94293$63c30240$0201a8c0@Richard><003401c94296$7d84c2b0$6400a8c0@Ken1><49172A08.2080005@san.rr.com><73DCEA0D-4BC9-46A1-B1B1-0461BB277372@vizachero.com><00a101c942a8$20e30e60$6400a8c0@Ken1>
In-Reply-To: <00a101c942a8$20e30e60$6400a8c0@Ken1>
All the SNPs in dbSNP have, by definition, been found to be
polymorphic in some sample by some researcher.
But that is, on its own, not enough to get it on to the YCC (or any
other tree). Often the submission to dbSNP does not include enough
information that someone else could come along and figure out where in
the tree to test the SNP for robustness.
For example, the original discovery of M228 was in an African E1b1a7
but recently turned up in a Italian R-U152.
And with the most downstream SNPs, you could test a SNP like P311 on a
large group of European R1b folks before you figured out that it was
phylogenetically useful (i.e. not merely equivalent to M269 itself).
Scientists have left a lot of meat on the table, so to speak, and the
value of chips like 23andMe and deCODEme is that we can put a lot of
those SNPs in the right context pretty quickly and relatively
inexpensively (compared, say, to sequencing all 2,000 individually).
VV
On Nov 9, 2008, at 3:17 PM, Ken Nordtvedt wrote:
> So I don't understand why
> they all did not appear in YCC or someone's tree.
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| Re: [DNA] L21 and P66 by Vincent Vizachero <> |