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Archiver > GENEALOGY-DNA > 2008-11 > 1226272381
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Subject: Re: [DNA] L21 and P66
Date: Mon, 10 Nov 2008 00:13:01 +0100 (CET)
In-Reply-To: <BAY111-DAV8C3F606B17F5C0ED73F71B11B0@phx.gbl>
That is very good point, I think!! Seeing so many new SNPs in R1b and I haplogroup found in 23andMe chip, I originally thought that for new R1a SNPs differentiation we just need more R1a people to be tested by this chip. But the problem can be one level lower – maybe R1a samples were not enough represented, (if at all), even in original set of samples used for suggestion of SNPs for the chip.
So maybe trying to force more people to order these tests would only be waist of time and their money, (at least according to Y-SNPs research).
We would need some chip, which is better “balanced”. Yes, somebody mentioned tens of thousands dollars for the order of the customized chip, but the tests are expensive enough to return this money very quickly to the company.
Does anybody know if what is the difference between 23andMe and DeCode chip from this point of view?
Jiri
> ------------ Původní zpráva ------------
> Od: Lawrence Mayka <>
> Předmět: Re: [DNA] L21 and P66
> Datum: 09.11.2008 19:29:49
> ----------------------------------------
> This is why no one should be promising that 23andMe testing will bring scads
> of useful SNPs to every haplogroup willing to spend $400 a pop and sell
> their DNA to a drug company. I suspect that 23andMe's SNPs were chosen
> based on their differentiation among Utahans, Yorubans, Chinese, and
> Japanese. Thus, 23andMe results may find plenty of useful SNPs in R1b,
> E1b1a, and O, but not necessarily any in other haplogroups.
>
> > [mailto:] On Behalf Of Ken Nordtvedt
> > The thing many may not know, 23andMe are not 2040
> > random y snps; they
> > are picked from a process and for a purpose which biases
> > their presence in
> > various haplogroups.
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