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Archiver > GENEALOGY-DNA > 2009-06 > 1244003356


From: Gary Felix <>
Subject: Re: [DNA] revised TMRCA calcuations for the R-L21 results
Date: Tue, 2 Jun 2009 21:29:16 -0700 (PDT)


What makes you believe your estimates are drift free and unbiased by allele length given the propensity to drift described by geneticists and recent studies on directional and mutational bias in allele length?

Gary
Mexico DNA Project Admin.

--- On Tue, 6/2/09, Vincent Vizachero <> wrote:

From: Vincent Vizachero <>
Subject: Re: [DNA] revised TMRCA calcuations for the R-L21 results
To:
Date: Tuesday, June 2, 2009, 9:09 PM

As I've already explained,  the TMRCA estimates aren't low because of 
effective population size.  It is the actual TMRCA that is lower.

I never said anything about "larger datasets" yielding "more accurate" 
estimates.  In fact, accurate estimates are possible with quite small 
datasets.  Longer haplotypes DO generally result in more accurate 
estimates than short haplotypes, but as you say even very short 
haplotypes are often useful.

VV



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