GENEALOGY-DNA-L ArchivesArchiver > GENEALOGY-DNA > 2009-07 > 1247928361
From: Nelda Percival <>
Subject: Re: [DNA] DNA Research;Research from D. Vanek and colleagues provide new insights intoDNA research
Date: Sat, 18 Jul 2009 09:46:01 -0500
This is very interesting.Isn't it the first steps in the direction of analysising the Y chromosomes of ancient human remains..
> Date: Fri, 17 Jul 2009 00:52:00 -0700
> Subject: [DNA] DNA Research; Research from D. Vanek and colleagues provide new insights into DNA research
> DNA Research; Research from D. Vanek
> and colleagues provide new insights into DNA research
> 351 words
> 20 July 2009
> Proteomics Weekly
> (c) Copyright 2009 Proteomics Weekly via NewsRx.com
> 2009 JUL
> 20 - (NewsRx.com) -- In this recently published study, investigators in Prague,
> Czech Republic conducted a study "To develop novel DNA extraction and
> typing procedure for DNA identification of the 7th century human remains,
> determine the familiar relationship between the individuals, estimate the
> Y-chromosome haplogroup, and
> compare the Y-chromosome haplotype with the contemporary populations. DNA from
> preserved femur samples was extracted using the modified silica-based
> extraction technique."
> chain reaction amplification was performed using human identification kits
> MiniFiler, Identifiler, and Y-filer and also laboratory-developed and validated
> Y-chromosome short tandem repeat (STR) pentaplexes with short amplicons. For
> 244A, 244B, 244C samples, full autosomal DNA profiles ( 15 STR markers and
> Amelogenin) and for 244D, 244E, 244F samples, MiniFiler profiles were produced.
> Y-chromosome haplotypes consisting of up to 24 STR markers were determined and
> used to predict the Y-chromosome haplogroups and compare the resulting
> haplotypes with the current population. Samples 244A, 244B, 244C, and 244D
> belong to Y-chromosome haplogroup
> R1b and the samples 244E and 244F to haplogroup
> G2a. Comparison of ancient haplotypes with the current population yielded
> numerous close matches with genetic distance bellow 2. Application of forensic
> genetics in archaeology enables retrieving new types of information and helps
> in data interpretation," wrote D. Vanek and colleagues.
> researchers concluded: "The number of successfully typed autosomal and
> Y-STR loci from ancient specimens in this study is one of the largest published
> so far for aged samples.."
> Vanek and
> colleagues published their study in Croatian Medical Journal (Kinship and
> Y-Chromosome Analysis of 7th Century Human Remains: Novel DNA Extraction and
> Typing Procedure for Ancient Material. Croatian Medical Journal,
> additional information, contact D. Vanek, Forens DNA Service, Janovskeho 18, Prague 17000 7, Czech
> publisher of the Croatian Medical Journal can be contacted at: Medicinska
> Naklada, Vlaska 69, HR-10000 Zagreb, Croatia.
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