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Archiver > GENEALOGY-DNA > 2009-08 > 1250121562


From: "Ken Nordtvedt" <>
Subject: Re: [DNA] Y-chromosomes of Jewish priests (2009 paper)
Date: Wed, 12 Aug 2009 17:59:22 -0600
References: <200908122351.n7CNpHYq031236@mail.rootsweb.com>


If you have a bunch of haplotypes selected by having the 12 marker CMH, you
can't then use the 12 markers that screened for the haplotypes as part of
the variance; they will all contribute zero by your choice. You have to
take out the mutation rates of the markers used for the selection.

----- Original Message -----
From: "Tim Janzen" <>
To: <>
Sent: Wednesday, August 12, 2009 5:51 PM
Subject: Re: [DNA] Y-chromosomes of Jewish priests (2009 paper)


> Dear Lawrence,
> I took your advice and did an interclade TMRCA calculation using the
> 4 Cohanim 67-marker haplotypes that are in the FTDNA haplogroup J project
> that have the 12-marker extended CMH with the exception of having DYS
> 439=11
> and compared them with the 12 Cohanim 67-marker haplotypes that have the
> 12-marker extended CMH. All 16 samples have been SNP tested and found to
> be
> in haplogroup J1. I got the following the ages with various versions of
> my
> program:
> 50 markers: 1565
> 24 slow markers: 1840
>
> I also ran an interclade TMRCA calculation using the 16 Cohanim
> 67-marker haplotypes mentioned above and compared them with the 6
> available
> J1e (J-L147+) Jewish 67-marker haplotypes in Cluster A with YCAII=22-22
> that
> are in the FTDNA haplogroup J project at
> http://www.familytreedna.com/public/Y-DNA_J/default.aspx. I got the
> following the ages with various versions of my program:
> 50 markers: 3699
> 24 slow markers: 3994
>
> The intraclade TMRCA calculation for the 6 J1e (J-L147+) Jewish
> 67-marker haplotypes in Cluster A with YCAII=22-22 was as follows:
> 50 markers: 1450
> 24 slow markers: 1671
>
> If I add the 5 available J1e (J-L147+) Jewish 67-marker haplotypes
> with YCAII=22-22 in Cluster C to those mentioned above in Cluster A and
> then
> compare them to the 16 Cohanim 67-marker haplotypes mentioned above by
> calculating an interclade TMRCA estimate, I get the following the ages
> with
> various versions of my program:
> 50 markers: 4056
> 24 slow markers: 4326
>
> I also compared the 5 available J1e (J-L147+) Jewish 67-marker
> haplotypes in Cluster C with YCAII=22-22 to the 6 mentioned above in
> Cluster
> A. I got the following the interclade TMRCA estimates with various
> versions
> of my program:
> 50 markers: 2906
> 24 slow markers: 6142
>
> I also compared the 9 available Jewish J1e 67-marker haplotypes that
> have YCAII=19-22 in Cluster A to 4 Jewish J1e 67-marker haplotypes that
> have
> YCAII=19-22 in Cluster B. I got the following the interclade TMRCA
> estimates with various versions of my program:
> 50 markers: 9181
> 24 slow markers: 13023
>
> Sincerely,
> Tim Janzen
>
>
> -----Original Message-----
> From:
> [mailto:] On Behalf Of Lawrence Mayka
> Sent: Wednesday, August 12, 2009 2:47 PM
> To:
> Subject: Re: [DNA] Y-chromosomes of Jewish priests (2009 paper)
>
> 1) Because of the phenomenal growth of the Ashkenazi Jewish community in
> the
> 1500-1939 era, any coalescence (intraclade) calculation is going to be
> heavily biased. I suggest instead an interclade calculation between the
> principal J-P58 Cohanim clusters of various historical Jewish communities.
>
>
>
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