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From: "Ken Nordtvedt" <>
Subject: [DNA] Fw: DNA] Variance Assessment of R:U106 DYS425Null Cluster
Date: Fri, 5 Feb 2010 21:41:53 -0700


----- Original Message -----
From: "Ken Nordtvedt" <>
To: <>
Sent: Friday, February 05, 2010 9:39 PM
Subject: Re: [DNA] DNA] Variance Assessment of R:U106 DYS425Null Cluster


>
> ----- Original Message -----
> From: "Anatole Klyosov" <>
> If mutation counting is very mysterious to you, how can we go
>> further?
>
> What you call mutation counting is mysterious to me. Suppose you have a
> collection of ten haplotypes of 4 STRs
> They are shown below with counts of each haplotype variation. I can count
> number of STR differences from an assumed intial haplotype
> which shows four copies. But I personally would not consider that a count
> of the number of mutations. Some of those differences are probably the
> consequences of a singular past mutation.
>
> So is your "mutation count" in this example seven (7) or ten (10)?
>
> (4) 10 10 10 10
> (1) 10 10 9 10
> (2) 10 11 10 10
> (1) 10 9 11 9
> (2) 10 9 10 9
>
> Ken



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