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Archiver > GENEALOGY-DNA > 2010-02 > 1265503766


From: Doug McDonald <>
Subject: Re: [DNA] odd mutation marker
Date: Sat, 06 Feb 2010 18:51:44 -0600
References: <50949.1265486350@connpoint.net><BAY133-W6307E4E222575B11C902AF1530@phx.gbl>
In-Reply-To: <BAY133-W6307E4E222575B11C902AF1530@phx.gbl>


William Hurst wrote:
> Hi Cornelia and all,
>
> You have a heteroplasmy at 16093. That means your mtDNA has a combination of the Cambridge
> Reference Sequence's T variant and the normal mutation's C variant. FTDNA only calls a
> heteroplasmy if each variant is at least 30% of the DNA. "Y" is simply the code for the
> combination of C and T. 16093 is the most heteroplasmic position in HVR1. You might also see
> 16093N, where the "N" means a heteroplasmy of undetermined variants. In reality, those are older
> sequences before FTDNA started assigning the codes; so in this case it's the same as "Y." See the
> FTDNA FAQ at: https://www.familytreedna.com/faq/answers/10.aspx
>
> For Mitosearch, just ignore the 16093 position; you are about equally as likely to be related to
> someone with or without 16093C.
>
>

I don't think ignoring it is correct: you should try both variants (i.e. not listing it
as a mutation, and listing it as a T). If you don't try list it as a T, you may miss
peoplw who are T and have too many other mutations.

Doug McDonald


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