GENEALOGY-DNA-L ArchivesArchiver > GENEALOGY-DNA > 2010-02 > 1265652060
Subject: [DNA] Dupuytren's contracture
Date: Mon, 8 Feb 2010 13:01:00 EST
In a message dated 2/8/2010 8:40:18 AM Pacific Standard Time,
> There may be more than one cause of DC. Perhaps someone familiar with
> the 23andMe test could comment on whether that test could show whether you
> have the same mutation found in the Swedish family.
The specific mutation wasn't identified, just localized somewhat to a
region of about 6 cM near the centromere of chromsome 16, containing many genes.
It might be possible for families who have members with and without the
condition to see where their mutation is localized, as I wrote in my recent
'Satiable Curiosity column "Mix and Match: DNA Stories from an Ancestor."
If there is a single common mutation (founder effect), more distant cousins
would share DNA in the same vicinity. Whether this would be extensive
enough to show up on Relative Finder would be a function of how long ago the