Archiver > GENEALOGY-DNA > 2010-02 > 1265922099

From: Robert TarĂ­n <>
Subject: Re: [DNA] News item: first ancient human genome sequenced
Date: Thu, 11 Feb 2010 15:01:39 -0600
References: <><COL123-DS63C151F2444DD7C7CC18AC84E0@phx.gbl><3271030599658703088@unknownmsgid><><SNT115-W46D09A2D7E2D2EC5512738CC4E0@phx.gbl>
In-Reply-To: <SNT115-W46D09A2D7E2D2EC5512738CC4E0@phx.gbl>

Didn't it say "tuft of hair" and wouldn't a tuft include attaching skin
probably containing the hair roots as well? opposed to loose hairs.

On Thu, Feb 11, 2010 at 2:43 PM, Steven Bird <>wrote:

> From:
> "DNA from cells associated with the root can be extracted and used for DNA
> analysis. Analysis of the DNA in the nucleus of the cell can be used for
> determining identity and DNA from the y-chromosome focuses on questions of
> paternity. Mitochondrial DNA is useful for establishing maternity. In
> theory, a single cell contains sufficient DNA to use for DNA analysis and so
> a single hair should provide the material required. In practice, a variety
> of complications make DNA testing of hair more complex. Roots of hair in the
> anogen (growth) phase contain more DNA than hairs from the telogen (resting)
> phase. However, hairs in the telogen phase are more likely to fall out
> passively. In addition, contamination issues are important as dead skin
> cells, which are also shed passively, contain DNA and may be collected from
> surfaces along with hair. If a hair from the telogen phase is collected, it
> may not contain enough nuclear DNA for analysis, but it might contain
> mitochondrial DNA. If the!
> hair has been forcibly removed, then pieces of tissue may be attached and
> DNA analyses can usually be run easily on these tissue cells."
> That's getting to the root of it. :-))

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