Archiver > GENEALOGY-DNA > 2010-02 > 1266348628

From: "Sandy Paterson" <>
Subject: Re: [DNA] TMRCA assessments
Date: Tue, 16 Feb 2010 19:30:28 -0000
References: <> <A597BD8569E24290A10B37465204E6B5@anatoldesktop> <525460709C6A493EBD3D6BECD514B319@john><>
In-Reply-To: <>

Hello John

I'm worried that I may not be treating multi-copy markers correctly in the
simulation software I've written.

Below you say that the CDY rates agree with yours at .017. Yet at

you show a rate of .03531.

Should I divide by the number of copies, namely 2 in this case to get

Many thanks


-----Original Message-----
[mailto:] On Behalf Of John Chandler
Sent: 15 February 2010 00:09
Subject: Re: [DNA] TMRCA assessments

John wrote:
> I have not checked what the current estimates of mutation rates are on the
> faster markers, and they may have changed a bit from when I originally
> extracted data. However, some time ago, the following was quoted as the
> mutation rates for the following markers...
> DYS576= 0.015 (1 mutation every 66 transmissions)
> DYS570= 0.014 (1 mutation every 71 transmissions)
> CDYa= 0.017 (1 mutation every 59 transmissions)
> CDYb= 0.017 (1 mutation every 59 transmissions).

These CDY rates agree with mine, but the other two are rather higher
than mine. Nonetheless...

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