GENEALOGY-DNA-L ArchivesArchiver > GENEALOGY-DNA > 2010-02 > 1267025278
From: William Hurst <>
Subject: Re: [DNA] mtDNA X1 in Eastern Europe
Date: Wed, 24 Feb 2010 10:27:58 -0500
Hi Lawrence and all,
> (known X2b, Ashkenazi, plus 2 more who match HVR1+HVR2)
> (Ashkenazi unlikely)
> So perhaps we are to conclude that:
> 2) Control-region mutations on the official phylotree for X should be
That conclusion is too broad, in my opinion. I know nothing about haplogroup X, but highly recurrent control-region (HVR) mutations such as 146C, 152C and 195C have multiple roles in haplogroup K and probable other subclades. In some places they are very good at defining subclades; in other places they are just random. And almost any mtDNA mutation, control- or coding-region, is subject to back mutation. But there are many extremely useful and reliable control-region mutations. If a K has 16T, 497T, 498-, 512C, 16048A, 16320T, 16234T, 16245T, 16319A, 16524G, etc., I can usually predict his subclade. If you have one particular combination of three recurrent HVR1 mutations, I can reliably say that your ancestors were from Iberia.
So, please don't ignore HVR mutations. Study them instead.
|Re: [DNA] mtDNA X1 in Eastern Europe by William Hurst <>|