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From: Kamel GAZZAH <>
Subject: [DNA] Linking Y Chromosome haplogroups with Sperm Motility
Date: Thu, 11 Mar 2010 10:44:35 +0000 (GMT)


Hi All
I was thinking about a possible relationship between Y chromsome and Sperm motility which is an important factor affecting men fertility.
I found this article http://www.eupedia.com/europe/origins_haplogroups_europe.shtml
which suggests that R1b haplogroup was successfull in European people relacement during the Bronze age thanks to its height sperm motility which allows heigher fertility, more children and power.

I was looking on this subject and found this article http://hmg.oxfordjournals.org/cgi/reprint/10/18/1873.pdf
which tried to find a relationship between Y chromosome haplogroups and motility
This article is quite old, published in 2001 and it does not talk about today known Y chromsome haplogroups.
They used the follwoing binary markers to build 4 haplogroups:
92R7 (C=>T),M9(C=>G) and SRY-1532(A=>G)

-M9 is a snp found in Haplogroup K
- For 92R7 and according to http://ymap.ftdna.com/cgi-bin/gbrowse/hs_chrY/?name=92R7
there are two SNP 92R7

92R7_192R7 ChrY:6.166..6.166 Mbp (1 bp) score=12.94
92R7_292R7 ChrY:10.36..10.36 Mbp (1 bp) score=12.94 92R7_1 is G to A and is found in P haplogroup
92R7_2 is G to A and is found in P haplogroup
I did not find an information about linking SRY-1532 to YCC haplogroups but this is an article about it
http://muse.jhu.edu/login?uri=/journals/human_biology/v073/73.1ramana.pdf

They identified that in one haplgroup Hg26+ , men have height percentage of azospermia or oligozoospermia.
Another study indicated that Hg26+ is presnet in Norway with a percentage of 4.6%
The question is to which YCC haplogroup, the Hg26+ can be identified ?
It seems to be YCC haplogroup K*

This is confirmed by another more recent article (2007) about linking Y haplogroup to sperm motility in chinese population: http://www.springerlink.com/content/952g18066707v851/
It found also that men belonging to Haplogroup K* might bear a risk factor of male infertility
But it is not clear to which specific sub-group of K haplogroup, this associaction was found.
Kamel Gazzah





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