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Archiver > GENEALOGY-DNA > 2010-03 > 1268361145


From: (John Chandler)
Subject: Re: [DNA] Genome work ushers in new genetic era- how can wemine new data?
Date: Thu, 11 Mar 2010 21:32:25 -0500
References: <820524.38859.qm@web31507.mail.mud.yahoo.com><3480483d1003111516m21fc9650j471e81b2393618ac@mail.gmail.com><6086D865ECC142D08C3655B4A6581FD5@john><792174.52375.qm@web81705.mail.mud.yahoo.com>
In-Reply-To: <792174.52375.qm@web81705.mail.mud.yahoo.com> (message from WayneKauffman on Thu, 11 Mar 2010 17:17:42 -0800 (PST))


Wayne wrote:
> Come up with a way for 23andMe to release all of their y chromosome
> data in order for it to be scanned for new SNPs.

23andMe doesn't do sequencing, just probing of a specific list of
already known and already studied SNPs. For the Y chromosome, I count
just 1921 SNPs reported. If we assume that they have tested 15,000
customers with Y chromosomes, the total output is only about equal to
the total number of sequenced bases in one Y chromosome. That means
there should be only a handful of novel, parallel mutations in the
whole lot. I don't know what the error rate is for their testing,
but I fear there might well be a similar handful of errors among so
many tests.

John Chandler


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