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Archiver > GENEALOGY-DNA > 2010-03 > 1268430172


From: Robert Stafford <>
Subject: Re: [DNA] NPE questions - also - can or should I use DNA cardsample for Family Finder?
Date: Fri, 12 Mar 2010 15:42:52 -0600
References: <8CC8F5F6122EC2F-1ED0-2DBD@webmail-m013.sysops.aol.com>
In-Reply-To: <8CC8F5F6122EC2F-1ED0-2DBD@webmail-m013.sysops.aol.com>


I looked at the McQuillen results at FTDNA. I think the lack of a match may
be because there are so few results in the project. There are only 15
participants, at least 2 different haplogroups and maybe 6 different
families.

Bob Stafford



On Thu, Mar 11, 2010 at 12:25 PM, <> wrote:

>
> I suspect an NPE in my Y-DNA line due to no close in surname matches
> (McQuillen) and a recent 66/67 match with another surname (Sutherland).
> Last fall, I tested at 23andMe. I've got 147 "cousins" there including a
> predicted 2d, and have beenhoping some would turn out to be through my
> father's side and give me aclue where the NPE comes in. Have had the usual
> problems with lack of responses and contacts that can't or won't provide any
> genealogical information, though that has been improving recently a bit, and
> the current TV programs may perhaps stimulate additional interest there down
> the road.
>
> I had been thinking of having my mother(still living) do the same test
> there so that I'd know which of mymatches came from her side, and thus by
> elimination would know which were frommy dad's.
>
> Now that FTDNA is rolling out Family Finder, there are several alternative
> approaches to choose from in trying to solve the NPE with autosomal
> matching, and they can be combined in various ways. I can't afford to test
> myself and both parents in both places, and with the complicated variables
> involved, I'm not sure what approach makes the most sense. So I'm
> soliciting informed opinion about what others might do in this situation.
>
> One option is for me to just test my own DNA again using Family Finder. (I
> have a pre-rollout invitation I can use).
>
> Another option is to test my mother at 23andMe, which would permit me to
> tell which of my matches there (by elimination) were through my father. Or,
> I could wait to test her at FTDNA when Family Finder has its public rollout,
> but unless I had also tested at FTDNA, this might not be terribly if there
> is a great difference in the list of SNPs being tested.
>
> The most compelling option, but no doubt the most uncertain and potentially
> most expensive, could be to try to test my deceased father's autosomal DNA
> in Family Finder. Just before he died, I sealed away a sample of his DNA on
> a DNA storage card. The card is now five years old. Does anyone know if it
> is likely enough DNA could be amplified out of such a card to work for SNP
> testing on a chip? And if I did this, could enough be amplified that some
> could be retained by FTDNA against other future test options, or would I
> have to assume that this would exhaust the DNA I have from him? On the flip
> side, is a card-stored sample going to be viable much longer anyway?
>
> Of course I might do various combinations of these tests. Some choices are
> also hard to evaluate because I don't really know whether pricing will
> change dramatically after Family Finder's public roll out; if, when, and at
> what cost FTDNA may eventually permit uploads of 23andMe data; and just what
> the differences are going to be between the FTDNA and 23andMe tests and
> database features. Any information or suggestions bearing on this will be
> appreciated!
>
> I'd also appreciate any comments anyone may wish to make on the specific
> 66/67 match involved, particularly with respect to timing. So far, I can't
> find any of my match's relatives anywhere near the vicinity of my male line
> ancestors back more than 10 generations, and if that's true, we are looking
> at some pretty long odds, which make me nervous I'm possibly missing
> something else, like a secondary NPE. But perhaps the FTDNA TIP
> predictions are skewed too recent in the context of the specific haplos.
> I'm R1b1b2a1b*, and my 67 marker results can be seen on Y-Search under
> 6EQXG. The mismatch is at DYS520, where I have 20 and he has 21.
>
> Thanks for any suggestions, information or recommendations!
>
>
>
>
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