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Archiver > GENEALOGY-DNA > 2010-03 > 1268744053


From: Vincent Vizachero <>
Subject: Re: [DNA] Clades, Definitions, Discoveries, FTDNA
Date: Tue, 16 Mar 2010 08:54:13 -0400
References: <201003160618.o2G6ICxX018421@mail.rootsweb.com>
In-Reply-To: <201003160618.o2G6ICxX018421@mail.rootsweb.com>


I think this is the source I was remembering.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748900/

> Twelve mutations were confirmed in ~10.15 Mb; eight of these had
> occurred in vitro and four in vivo. The latter could be placed in
> different positions on the pedigree and led to a mutation-rate
> measurement of 3.0 × 10−8 mutations/nucleotide/generation (95% CI:
> 8.9 × 10−9–7.0 × 10−8), consistent with estimates of 2.3 ×
> 10−8–6.3 × 10−8 mutations/nucleotide/generation for the same Y-
> chromosomal region from published human-chimpanzee comparisons [5]
> depending on the generation and split times assumed.


VV


On Mar 16, 2010, at 2:18 AM, Tim Janzen wrote:

> Do you have some recent data on which you are projecting the SNP
> mutation rate to be 1-in-30 million bps on the Y? The last time I
> looked at
> this I was coming up with estimates of about one SNP every 4-6
> generations.



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