GENEALOGY-DNA-L Archives

Archiver > GENEALOGY-DNA > 2010-03 > 1268899306


From: Anders Pålsen <>
Subject: Re: [DNA] New estimate for human mutation rate
Date: Thu, 18 Mar 2010 01:01:46 -0700 (PDT)
In-Reply-To: <COL123-DS245B553DCF0F1AD919A5F7C82B0@phx.gbl>


So is it Zhiv or germline?

Anders

--- Den tor 2010-03-18 skrev RICHARD KENYON <>:

> The following appeared in today's
> on-line version of Nature.
> GENOMICS
>
> We are family
>
> Science doi:10.1126/science.1186802 (2010)
>
> The human mutation rate is lower than previously thought,
> according to researchers who sequenced the entire genomes of
> four family members - two siblings with rare
>
> genetic disorders, and their parents. David Galas and Leroy
> Hood at the Institute for Systems Biology in Seattle,
> Washington, and their colleagues estimate that
>
> roughly 70 new mutations arise per genome between
> generations. This is lower than earlier estimates based on
> genomic comparisons between humans and their
>
> closest living relatives, chimpanzees. The team also
> pinpointed four genes likely to underlie the siblings' two
> disorders - Miller syndrome and primary ciliary
>
> dyskinesia. The four genes are a subset of those reported
> in previous studies.
>
> For a longer story on this research, see
> go.nature.com/Owe9CD
>
>
> Richard R. Kenyon ("Dick")
>
> -------------------------------
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