GENEALOGY-DNA-L ArchivesArchiver > GENEALOGY-DNA > 2010-03 > 1268922229
From: Steven Bird <>
Subject: Re: [DNA] New estimate for human mutation rate
Date: Thu, 18 Mar 2010 10:23:49 -0400
Neither. It's the whole genome not just the Y.
> Date: Thu, 18 Mar 2010 01:01:46 -0700
> Subject: Re: [DNA] New estimate for human mutation rate
> So is it Zhiv or germline?
> --- Den tor 2010-03-18 skrev RICHARD KENYON <>:
> > The following appeared in today's
> > on-line version of Nature.
> > GENOMICS
> > We are family
> > Science doi:10.1126/science.1186802 (2010)
> > The human mutation rate is lower than previously thought,
> > according to researchers who sequenced the entire genomes of
> > four family members - two siblings with rare
> > genetic disorders, and their parents. David Galas and Leroy
> > Hood at the Institute for Systems Biology in Seattle,
> > Washington, and their colleagues estimate that
> > roughly 70 new mutations arise per genome between
> > generations. This is lower than earlier estimates based on
> > genomic comparisons between humans and their
> > closest living relatives, chimpanzees. The team also
> > pinpointed four genes likely to underlie the siblings' two
> > disorders - Miller syndrome and primary ciliary
> > dyskinesia. The four genes are a subset of those reported
> > in previous studies.
> > For a longer story on this research, see
> > go.nature.com/Owe9CD
> > Richard R. Kenyon ("Dick")
> > -------------------------------
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