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Archiver > GENEALOGY-DNA > 2010-03 > 1268922229


From: Steven Bird <>
Subject: Re: [DNA] New estimate for human mutation rate
Date: Thu, 18 Mar 2010 10:23:49 -0400
References: <COL123-DS245B553DCF0F1AD919A5F7C82B0@phx.gbl>,<835736.54425.qm@web24507.mail.ird.yahoo.com>
In-Reply-To: <835736.54425.qm@web24507.mail.ird.yahoo.com>


Neither. It's the whole genome not just the Y.



Steve



> Date: Thu, 18 Mar 2010 01:01:46 -0700
> From:
> To:
> Subject: Re: [DNA] New estimate for human mutation rate
>
> So is it Zhiv or germline?
>
> Anders
>
> --- Den tor 2010-03-18 skrev RICHARD KENYON <>:
>
> > The following appeared in today's
> > on-line version of Nature.
> > GENOMICS
> >
> > We are family
> >
> > Science doi:10.1126/science.1186802 (2010)
> >
> > The human mutation rate is lower than previously thought,
> > according to researchers who sequenced the entire genomes of
> > four family members - two siblings with rare
> >
> > genetic disorders, and their parents. David Galas and Leroy
> > Hood at the Institute for Systems Biology in Seattle,
> > Washington, and their colleagues estimate that
> >
> > roughly 70 new mutations arise per genome between
> > generations. This is lower than earlier estimates based on
> > genomic comparisons between humans and their
> >
> > closest living relatives, chimpanzees. The team also
> > pinpointed four genes likely to underlie the siblings' two
> > disorders - Miller syndrome and primary ciliary
> >
> > dyskinesia. The four genes are a subset of those reported
> > in previous studies.
> >
> > For a longer story on this research, see
> > go.nature.com/Owe9CD
> >
> >
> > Richard R. Kenyon ("Dick")
> >
> > -------------------------------
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