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Archiver > GENEALOGY-DNA > 2010-06 > 1275416355


From: Sasson Margaliot <>
Subject: Re: [DNA] Re : Re : Possible alleles acquired by humans fromNeandertals after leaving Africa
Date: Tue, 1 Jun 2010 21:19:15 +0300
References: <728817.81948.qm@web25904.mail.ukl.yahoo.com><210055.73862.qm@web25902.mail.ukl.yahoo.com><AANLkTik0BpQz6FAdQ0em-SCWj_6RsCJqegsxfgsAmjxq@mail.gmail.com><BAY122-W1C806504F6B6645E9DA89DAEF0@phx.gbl>
In-Reply-To: <BAY122-W1C806504F6B6645E9DA89DAEF0@phx.gbl>


Acrobatic fairy tales, indeed.

Some academics certainly think that interbreeding is "strong possibility",
but we here jump and accept it as a accomplished fact, referring to the
proto-Eurasian variants as "Neanderthal".

And THAT is ridiculous.




On Tue, Jun 1, 2010 at 6:02 PM, Jackson Montgomery-Devoni <
> wrote:

>
>
>
> ''Acrobatic fairy tales eh''? ''By the way, no major academic authority had
> so far endorsed the wild
> "Out-of-Africa interbreeding" interpretation of the new data.''
>
>
>
> It seems to me that the new paper by Green supports the interbreeding
> hypothesis. I see that you are a firm non believer in this but those
> acaemics think that interbreeding is a strong possibility. Now they may be
> wrong yes but also they may be right.
>
>
>
>
>
>
>
> Jackson
>
>
> > Date: Tue, 1 Jun 2010 10:04:49 +0300
> > From:
> > To:
> > Subject: Re: [DNA] Re : Re : Possible alleles acquired by humans from
> Neandertals after leaving Africa
> >
> > The Out-of-Africa hypothesis was formulated as a guess based on
> > insufficient, preliminary and partial data, available at the time, in
> > absence of archaic human DNA.
> >
> > Now, with the archaic human DNA available, the identity of the earliest
> > modern humans becomes clear too - they are Eurasians, which are less
> > divergent from the archaic humans. (Eurasians also have higher DNA
> diversity
> > than Sub-Saharan Africans).
> >
> > An attempt to hold on Out-of-Africa hypothesis leads to acrobatic,
> > fairy-tale style stories about "interbreeding on the way trough Middle
> > East". Just let go.
> >
> > Sub-Saharans were in deep isolation until "rediscovered" by
> Bantu-expansion.
> > This naturally explains both divergence and reduced diversity.
> >
> > So there is no need to attribute the ancestral, Eurasian DNA
> "Neanderthal".
> >
> > By the way, no major academic authority had so far endorsed the wild
> > "Out-of-Africa interbreeding" interpretation of the new data.
> >
> >
> >
> >
> >
> >
> > On Tue, Jun 1, 2010 at 6:42 AM, vernade didier <
> >wrote:
> >
> > >
> > > Jackson,
> > >
> > > Here is the link :
> > >
> > >
> http://spittoon.23andme.com/2010/05/06/new-evidence-suggests-interbreeding-between-humans-and-neanderthals/
> > >
> > > Here are the "non african" alleles :
> > > rs10915846 = A
> > > rs11792454 = T
> > > rs17324630 = C
> > > rs17324756 = C
> > > rs10971319 = A
> > > rs1556249 = T
> > > rs10971346 = T
> > > rs1330692 = C
> > >
> > > As for myself I am not sure at all that "non african" means a
> Neanderthal
> > > origin. For what is written on these links the alleles above are the
> ones
> > > found in the Neanderthal genome. I didn't check.
> > >
> > > Didier
> > >
> > >
> > >
> > > >
> > > >
> > > > I compared my data to my mother’s data. I was looking at
> > > > the Chr 9 SNPs where it seems that my mother has a stretch
> > > > of “non african” SNPs in an intergenic region and this
> > > > stretch was passed to me . The SNPs are :
> > > > rs11792454 , rs17324630 , rs17324756 , rs10971319 ,
> > > > rs1556249 , rs10971346 and rs1330692 . We also both have
> > > > rs10915846 as “non african” ; this SNP is in the ENAH
> > > > gene . Apart from these the non african SNPs are rare. My
> > > > mother has an additional non african SNP in ENAH
> > > > (rs16845098) and I have one in CASC3 gene.
> > > > The stretch on Chr 9 may be rather common. I am curious to
> > > > know whether ENAH is also rather frequent and I suspect that
> > > > the other SNPs are much less frequent.
> > > >
> > > > Didier
> > > >
> > > > >
> > > > > At the 23andMe Spittoon blog of May 6 David Lonard
> > > > lists 42
> > > > > alleles by rs
> > > > > number that seem to be good candidates for having come
> > > > from
> > > > > the purported
> > > > > late infusion from Neandertals. These can be looked
> > > > up
> > > > > fairly quickly in
> > > > > the 23andMe raw data. I had 6 of the so-called
> > > > > out-of-Africa (OOA) alleles
> > > > > . Of these, I was homozygous for 1 (rs10915846) and
> > > > > heterozygous for 5. I
> > > > > don't have a firm opinion about the authenticity of
> > > > these
> > > > > 42 alleles as
> > > > > being Neandertal-derived, but checking them out can be
> > > > a
> > > > > fun exercise in
> > > > > any case.
> > > > >
> > > > > Obed
> > > > >
> > > >
> > > >
> > > >
> > > >
> > > >
> > > >
> > > >
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> > >
> > >
> > >
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