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From: "Alister John Marsh" <>
Subject: Re: [DNA] How old is Y-Chromosome Adam?..
Date: Wed, 5 Jan 2011 11:19:11 +1300
References: <201101021901.p02J1Pqr008512@mail.rootsweb.com>
In-Reply-To: <201101021901.p02J1Pqr008512@mail.rootsweb.com>


Tim,

I was just wondering what would happen if instead of doing different
calculations for panels of markers with higher or lower mutation rate, you
looked at other criteria to group markers.

For example, you could do the calculations for different marker groups which
had STRs of repeats of 3, or 4, or 5.

For example you could do the calculations for different marker groups which
had STRs which were predominantly made of repeats with C and T bases,
compared to repeats predominantly G and A bases, or mixed C, T, G, A bases.

For example you could do the calculations for different marker groups which
had STRs which were regular, ie all repeats of say CTTT, or of mixed
repeats, such as some CTTT, some CCTT, or a STR with regular repeats most of
the way through with perhaps a SNP in the middle of the repeat chain.

It may be that different results for haplogroup age estimates are linked to
differences in slow or fast markers, but it would be interesting to see if
any of the variation of the results is partially linked to other variables,
eg STRs with C & T repeats as opposed to G & A repeats. It would be good if
we could show that differences in estimates for haplogroup branches were
linked to factors other than mutation rate. If we get difference in
estimates for say C ad T repeats, compared to say G & A repeats when the
mutation rates are both equal, it would be something to think about.

John.


--------------------------------------------------
From: "Tim Janzen" <>
Sent: Monday, January 03, 2011 8:01 AM
To: <>
Subject: Re: [DNA] How old is Y-Chromosome Adam?

> Dear All,
> Yesterday I decided to do fresh calculations using various
> haplogroup A haplotypes that have become available recently. I chose 7
> FTDNA haplogroup A 67-marker haplotypes that had been confirmed by SNP
> testing and that were not from closely related people. ....etc.......

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