GENEALOGY-DNA-L Archives

Archiver > GENEALOGY-DNA > 2011-01 > 1294343477


From: Wilcox Lisa <>
Subject: Re: [DNA] Founder mutation for the "Irish Giant" (Ann Turner)
Date: Thu, 6 Jan 2011 11:51:17 -0800
References: <193971586.879946.1294341294129.JavaMail.root@sz0128a.westchester.pa.mail.comcast.net>
In-Reply-To: <193971586.879946.1294341294129.JavaMail.root@sz0128a.westchester.pa.mail.comcast.net>


Hi Paul--

This stuff is so outside the expertise of most admins, myself emphatically included!!

I've considered posting a statement (for a project that includes French-Canadians) briefly explaining founder effects, and referring those who may be concerned to a genetic counselor. Not because those mutations are likely to show up in Y results but because, if folks with this heritage aren't currently resident in Quebec, they may not be aware of the issues.


Lisa


On Jan 6, 2011, at 11:14 AM, wrote:

> As administrator of the Byrne project, I am getting emails from members asking if we can obtain the giant's (Charles Byrne 1761-1783)DNA. I have replied, "A mutation that produces a medical effect would have to be on one of the autosomal genes. The Y chromosome that we test carries no medical information. Even if it did, I would be reluctant to inform a project member that his son might grow to be seven feet tall, grow a tail, or whatever." Am I correct?
> That said, it would be interesting to know if any y-chromosome data was recovered. Does anyone have access to the article in the New England Journal of Medicine that was mentioned in the following?
> http://www.nytimes.com/2011/01/06/health/06giant.html?_r=2&scp=1&sq=charles%20byrne%20dna&st=cse
> Paul
>
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