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From: Didier VERNADE <>
Subject: Re: [DNA] Y-chromosome Adam 142 thousand years old;revised phylogeny
Date: Fri, 20 May 2011 15:20:06 +0200 (CEST)
References: <BANLkTimAbuJWejh1SDUiehF0mbv3wuhBhg@mail.gmail.com>
In-Reply-To: <BANLkTimAbuJWejh1SDUiehF0mbv3wuhBhg@mail.gmail.com>


Interesting. Recently (a few days ago), I posted "back to Africa" on this list with not a single answer. This new paper is indeed better than what I was reporting but I am surprised that no one had an interest in the subject ; so close to this awaited publication (I didn't know but many others awaited it as I understand).

Didier


> My post:
> http://dienekes.blogspot.com/2011/05/father-of-us-all-142-thousand-years-ago.html
>
> Paper:
> http://www.cell.com/AJHG/fulltext/S0002-9297(11)00164-9
>
> The American Journal of Human Genetics, 19 May 2011
> doi:10.1016/j.ajhg.2011.05.002
>
> A Revised Root for the Human Y Chromosomal Phylogenetic Tree: The
> Origin of Patrilineal Diversity in Africa
>
> Fulvio Cruciani et al.
>
> To shed light on the structure of the basal backbone of the human Y
> chromosome phylogeny, we sequenced about 200 kb of the male-specific
> region of the human Y chromosome (MSY) from each of seven Y
> chromosomes belonging to clades A1, A2, A3, and BT. We detected 146
> biallelic variant sites through this analysis. We used these variants
> to construct a patrilineal tree, without taking into account any
> previously reported information regarding the phylogenetic
> relationships among the seven Y chromosomes here analyzed. There are
> several key changes at the basal nodes as compared with the most
> recent reference Y chromosome tree. A different position of the root
> was determined, with important implications for the origin of human Y
> chromosome diversity. An estimate of 142 KY was obtained for the
> coalescence time of the revised MSY tree, which is earlier than that
> obtained in previous studies and easier to reconcile with plausible
> scenarios of modern human origin. The number of deep branchings
> leading to African-specific clades has doubled, further strengthening
> the MSY-based evidence for a modern human origin in the African
> continent. An analysis of 2204 African DNA samples showed that the
> deepest clades of the revised MSY phylogeny are currently found in
> central and northwest Africa, opening new perspectives on early human
> presence in the continent.
>
>
> --
> Dienekes' Anthropology Blog: http://dienekes.blogspot.com
> Dodecad Ancestry Project: http://dodecad.blogspot.com
>
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