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From: "Sandy Paterson" <>
Subject: Re: [DNA] Asymptotic Distributions for General Mutation Models
Date: Wed, 8 Jun 2011 19:05:45 +0100
References: <972D673E3D084E2DBBD515DD90077C82@kenPC>
In-Reply-To: <972D673E3D084E2DBBD515DD90077C82@kenPC>


That takes me back a bit.

The concept of a stationary population, as I recall, makes it easier to formulate some mathematical concepts that are useful as approximations to reality. An example is a population where births match deaths in such a way that the population size remains constant. You can take it further, and work on the assumption that the age distribution remaining constant as well (that may well be a prerequisite of the former).

When I had a go at reading Walsh's paper, I found it very heavy going and frankly, didn't understand much. However, I got the distinct impression that that's what the infinite alleles model is all about - it assumes some form of equilibrium that makes calculations easy but accuracy a myth. I'm sure you'll understand his paper more easily than I did.



-----Original Message-----
From: [mailto:] On Behalf Of Kenneth Nordtvedt
Sent: 08 June 2011 16:58
To:
Subject: [DNA] Asymptotic Distributions for General Mutation Models



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