GENEALOGY-DNA-L Archives

Archiver > GENEALOGY-DNA > 2011-06 > 1308950751


From: "Jacques Beaugrand" <>
Subject: Re: [DNA] Mtdna Hg K1a1b1a
Date: Fri, 24 Jun 2011 17:25:51 -0400
References: <BANLkTikiQozhMbJU5akL8Hc46moTj9fdhw@mail.gmail.com>
In-Reply-To: <BANLkTikiQozhMbJU5akL8Hc46moTj9fdhw@mail.gmail.com>


Robert

Please use your Internet Explorer browser and reach URL
http://phylotree.org/tree/subtree_U.htm

You'll see that K1a1b1a is a U8b with several downstream variations
(examine the Tree there starting at U8b and follow the branches down to
K1a1b1a).
It shows variations 10978 (an A was replaced by a G) 12954 (a T changed
into a C) and in the control region 16234 (C to T) and a reversion
has occured at position 114, that is one would have expected 114 to be
present
but it had reverted to its CRS state (thus showing no difference with the
rCRS at that position).

According to the information furnished by Phylotree.org access numbers
DQ301803, EU926147 at Genbanks would correspond to K1a1b1a cases

Here are these cases:

DQ301803 K1a1b1a
A73G A263G 315.1C C497T 523.1C 523.2A A750G T1189C A1438G A1811G A2706G
A3480G A4769G C7028T A8860G G9055A T9698C A10398G A10550G A10978G T11299C
A11467G A11470G G11719A G11914A A12308G G12372A T12954C C14167T C14766T
T14798C A15326G A15924G T16224C C16234T T16311C T16519C

and

EU926147 K1a1b1a
A73G C114T A263G 315.1C C497T A750G T1189C A1438G A1811G A2706G A3480G
A4769G C7028T A8860G G9055A T9698C A10398G A10550G A10978G T11299C A11467G
A11470G G11719A G11914A A12308G G12372A T12954C C14167T A14203C A14517G
C14766T T14798C A15326G A15924G C16223T T16224C C16234T T16311C T16519C


If you have your FMG (the complete Mitochondrial Genome is sequenced) done
but it does not correspond to one of the above, please have it registered
at Genbank.

These FMGs were described (still according to PhyloTree.org) by Behar
2006, 2008a and by Grzybowski 2007

Here are the references to theese papers.
Behar DM, Metspalu E, Kivisild T, Achilli A, Hadid Y, Tzur S, Pereira L,
Amorim A, Quintana-Murci L, Majamaa K, Herrnstadt C, Howell N, Balanovsky O,
Kutuev I, Pshenichnov A, Gurwitz D, Bonne-Tamir B, Torroni A, Villems R,
Skorecki K. 2006.
The matrilineal ancestry of Ashkenazi Jewry: portrait of a recent founder
event. Am J Hum Genet 78(3):487-497. http://dx.doi.org/10.1086/500307
Behar DM, Metspalu E, Kivisild T, Rosset S, Tzur S, Hadid Y, Yudkovsky G,
Rosengarten D, Pereira L, Amorim A, Kutuev I, Gurwitz D, Bonne-Tamir B,
Villems R, Skorecki K. 2008a. Counting the founders: the matrilineal genetic
ancestry of the Jewish Diaspora. PLoS ONE 3(4):e2062.
http://dx.doi.org/10.1371/journal.pone.0002062

Grzybowski T, Malyarchuk BA, Derenko MV, Perkova MA, Bednarek J, Wozniak M.
2007. Complex interactions of the Eastern and Western Slavic populations
with other European groups as revealed by mitochondrial DNA analysis.
Forensic Science International: Genetics 1(2):141-147.
http://dx.doi.org/10.1016/j.fsigen.2007.01.010

>From the reading of these papers you can infer that K1a1b1a could be Jewish,
Ashkenaze. No, it is not Amerindian.
K1a1b1a is clearly European, which is re-affirmed by Wikipedia:
http://en.wikipedia.org/wiki/Haplogroup_K1a1b1a_(mtDNA)


Hope this will help.

Bonne Saint-Jean-Baptiste

Jacques




This thread: