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From:
Subject: Re: [DNA] Markers that determine someone is Irish and Scottish
Date: Sat, 9 Jul 2011 11:33:05 EDT


Well, my Hopkins from County Mayo Ireland is L21*. Does not match so far
any other Hopkins.

They are also L302 and L319.1 positive which only one other unrelated man
(out of 120 men tested) is as well. They are negative for M222.

I found this excerpt from the article very interesting to me:
"There are at present five known non-private subgroups of R1b-S145 (M222,
S168, S169, S175 and S176, all seen in Ireland); none of these SNPs were
identified in the Irish individual and he potentially belongs to an as yet
undescribed sublineage within S145".

Can someone identify S168, S169, S175 and S176 to FTDNA SNPs? I'm
wondering if my paternal line fits this man's sublineage. My ancestral home in Mayo
was very rural (still is) and a bit isolated which would limit the marriage
pool.

I also wonder which other SNPs the individual is positive.

Thanks.
Nora Hopkins
Hopkins- McCabe cluster




In a message dated 7/9/2011 10:15:15 A.M. Eastern Daylight Time,
(mailto:) writes:

The full text of the technical article about the complete genome sequence
of
this Irishman is available online.

http://genomebiology.com/2010/11/9/R91

His sample was specifically selected as being typical for an Irishman from
a
previous study using a genome wide scan. It was based on an Illumina chip
with about 500,000 markers, similar to the one used by 23andMe and by FTDNA
for Family Finder / Population Finder. Figure S1 is a PC (Principle
Components) diagram, a way of showing how similar or different various
samples are. This dataset is not available to FTDNA or 23andMe.

The same article states that his Y-DNA tested positive for a SNP called
S145
( L21 at FTDNA). There is a Y-DNA signature that is commonly (but not
exclusively) found in Irish, which FTDNA calls "Niall of the Nine
Hostages."
It is positive for a SNP called M222, a subclade of L21. The sample in the
above paper was negative for that.

http://www.familytreedna.com/landing/matching-niall.aspx

Genetic genealogists continue to look for clusters of similar Y-STR
results,
so you may see terms like "Irish Type III."

Ann

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