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From: "Kenneth Nordtvedt" <>
Subject: [DNA] I1 Chromat Reader wanted?
Date: Thu, 29 Sep 2011 14:56:33 -0600


L593_1 and L593_2 are two snps on a palindrome. They showed up doubly derived (T+A+) on a recent WTY from AS1 L338 I1f
That would be an interesting recLOH event if it reversed both sites.
Different partial results have been reported on earlier WTY from I1xL22
A-T- is supposed to be the ancestral state.

I checked the most recent several I1 WTYs, and they all cover the two sites for these snps.
Is there someone who reads chromats and is interested in I1xL22 who would read these two snps for these few I1 WTYs?

I’d like to see if there seems any prospect to find a phylogenetically useful marker (pair) to seriously divide I1xL22. If it looks worthwhile, I’ll do the first order for the pair.
While the other haplogroups fly ahead with gluts of new snps found from their thickest bush, we have to be a bit more creative to find useful phylogenetic markers in I1xL22, even if they are not looked at kindly by the keepers of the holy trees.
If they serve a utilitarian purpose for further understanding of the phylogenetic order, that’s what really matters.
Other snps will come along in due time to tag just about every internode branch segment in the tree; but what “due time” means in I1-xL22 is not clear.

I can give someone the GRC numbers and the L593_1 and L593_2 locations if they will proceed to read these locations.
They are not supposed to be the easiest locations to read due to background stuff.

Ken



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