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Archiver > GENEALOGY-DNA > 2011-11 > 1320611288


From: RThrift <>
Subject: Re: [DNA] Any feedback on the RCC method of TMRCA estimates?
Date: Sun, 6 Nov 2011 12:28:08 -0800
In-Reply-To: <mailman.1080.1320605197.10215.genealogy-dna@rootsweb.com>


Sandy, please do, that's the point here.

FYI, part 2 of Howard's pair of papers is at
http://www.jogg.info/52/files/Howard2.pdf

Ken, just read it (part 1).

Once a matrix of pairwise correlation coefficients is set up (some details seem to be obscured in the paper), as Sandy mentioned each value is scaled: Take the reciprocal of the 'correlation coefficient' so calculated. Subtract 1. Multiply by 10,000. =RCC

But that's just the starting point. He in effect comes up with an overall mutation rate ("time scale") from known pedigree /haplotype data using the Hodges-Lehmann estimator and pairwise TMRCAs. 1 RCC = 43.3 years, SD ~ 8%.

He argues that the average RCC of a cluster is a good proxy for the MRCA of the cluster. Time to the common ancestor = 52.7 x (the average RCC of the cluster) (just read the paper!)

Richard Thrift


From: "Sandy Paterson" <alexanderpatterson@
...I could also easily show how the paper uses (abuses?) the concept in trying to apply it to two haplotypes.

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