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Archiver > GILBERT-DNA > 2007-02 > 1170940804


From: "Kate mullins" <>
Subject: Re: [GILBERT-DNA] Project Update
Date: Thu, 08 Feb 2007 08:20:04 -0500
In-Reply-To: <01ed01c74b1a$45766b50$6501a8c0@DellOffice>


Jane-Thanks for the update Kate


>From: "Jane Gilbert" <>
>Reply-To:
>To: "GilbertDNA" <>
>Subject: [GILBERT-DNA] Project Update
>Date: Wed, 7 Feb 2007 19:44:18 -0500
>
>Hi everyone!
>
>Time for an update.
>
>The project is now up to 38 participants. Well, I guess it's actually 39,
>but I don't yet have a lineage for the last person who has joined, so he
>doesn't yet have a spot on the project page. There are 23 unique lines to
>date. http://www.janegilbert.org/gilbertdna/results.htm
>
>The last time I e-mailed, I included this:
> Within the past couple of weeks, we've gotten two new participants
>bringing our total to 38. One of the new participants has roots in GA and
>AL and is hoping to connect with one of our already tested Southern lines.
>Here's his lineage:
>http://www.janegilbert.org/gilbertdna/ydnakits/davidga.htm
>
>Well, this participant was in luck. He was indeed at match with an
>existing line! The match was an interesting one, though. You'll see his
>results and his match towards the bottom of the results table in bright
>green.
>
>Note the darker green markers that indicate a mis-match. If you count
>them, you'll find six differences. That is outside what Family Tree DNA
>would consider to be match, but when I noticed the apparent "clumping" of
>the differences, I asked Family Tree DNA to take a look them. Below is the
>response I received. If you don't want to read the whole thing, the gist
>of it is that we should consider these two samples to have only three
>differences. The last two sentences of the response are also very
>enlightening. They suggest that you're more likely to see mutations take
>place between generations if the father is older.
> This is an interesting case. These two males have a genetic distance of
>one at CDY a and b (although it is counted as two, since there is a one
>step difference at Cdy a and b, it should be considered one) that is being
>scored as two. Additionally, current research has shown that mutations that
>occur at 464 and CDY a and b may occur at the same due to their location on
>the Y-DNA (close to the markers responsible for sperm genesis which seem to
>cause more mutations in the passing of mutations at 464 and CDY a and b) so
>while genetic distance is technically 5, I would consider the changes to
>have happened at 464 and CDY a and b to have happened at the same time and
>would list the genetic distance at 3 on these 37 markers.
>
> If another male descendent of either of the Georgia or Alabama lines can
>be tested it may shed some more light on this situation. Other factors
>that may contribute to mutations may be in play as well. Anecdotally we
>have seen that men born to older men may have a higher chance of receiving
>mutations from their father. In other words if one of these two men is
>descended from men who were the youngest of their line this may be
>affecting the rates of mutations passed along their lines.
>Anyway, the new found cousins are currently working together to try to find
>the connection. I'll update the new participant's line when he gets it
>all sorted out.
>
>That's all for now.
>
>Jane
>
>Gilbert Y-DNA Admin
>
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