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From:
Subject: Re: [DNA] There is no WAMH (R1b modal) cluster
Date: Tue, 13 Feb 2007 20:32:01 EST


In a message dated 2/13/2007 4:30:05 PM Pacific Standard Time,
writes:

> Could one of our mtDNA experts please comment as to whether the same thing
> has happened to mtDNA haplogroup H with full sequence testing i.e. there is
> no longer a large central cluster but rather a large number of distinct
> branches?
>

Yes, the master phylogenetic tree at MitoMap (which integrates coding region
data from a number of citations) shows just a few sequences at the core, with
a very large number of branches (some of which are quite deep and/or have more
exemplars than the central core) You'll need to zoom in a lot and then pan
across the bottom line of the chart:

http://www.mitomap.org/mitomap-phylogeny.pdf

Bryan Sykes has illustrations of mtDNA network diagrams on p 166 of "Adam's
Curse" (or Search Inside the Book at Amazon for keywords "contrasting cluster")

http://www.amazon.com/exec/obidos/ASIN/0393058964

His mtDNA diagram is H with HVR data only. I'd say full sequence data would
make the diagram look more like his Y example, where the central point is
smaller than some of the outlying branches.

Another way to check the Y data is to use the default values at SMGF -- the
modal value for each marker individually. That would be primarily R1b. The
closest match has two differences, and there are only a handful of those. That
doesn't show whether there are larger clusters, but it does show that the central
core is miniscule.

Ann Turner











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