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Archiver > GENEALOGY-DNA > 2007-02 > 1171594581


From: charles <>
Subject: Re: [DNA] Sources for information on YSTR haplotype mutation rates
Date: Thu, 15 Feb 2007 21:56:21 -0500
References: <KHEKIJEABJGJEKDPFEDMIEOEDDAA.elizabethod@eircom.net><1132CF4A-B306-404E-9C42-F55BBB0F76FF@vizachero.com>
In-Reply-To: <1132CF4A-B306-404E-9C42-F55BBB0F76FF@vizachero.com>


Vincent,

There are observed average YSTR haplotype mutation rates for dozens of surname
projects which have known descent trees and pedigrees from the MRCA in my YSTR
Mutation Rate Project. This is another early source for the range of average
mutation rates observed, and most frequently observed average mutation rates
observed, for various size haplotypes in various families and surname projects.
See my project website and the 37 marker haplotype histogram for more details.
http://www.ystrlog.org/

Charles Kerchner
Emmaus PA

Vincent Vizachero wrote:
> On Feb 15, 2007, at 5:40 PM, Elizabeth O'Donoghue wrote:
>>
>>
>>Ken, the mutation rates of Zhivotovsky are posted on John McEwan's
>>site
>>http://www.geocities.com/mcewanjc/p3asd.htm. They are not the same
>>as the
>>ones you mentioned. This is an indication of the disparity that I was
>>pointing out at the beginning of this discussion.
>
>
> The function of a TMRCA calculator is to establish the probability
> that two people share a common ancestor within a given (genealogical)
> period of time. Pedigree rates are the appropriate rates to input
> into a TMRCA calculator, and I don't think there is much dispute that
> the rates published by John Chandler in the Journal of Genetic
> Genealogy last fall are the best estimates of mutation rates for the
> most commonly used markers.
>
> Zhivotovsky et al. were looking at a different problem (estimating
> the age of populations) and the rates they use in their study are not
> appropriate inputs for a TMRCA.
>
> Vince

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